A Study Says Curbing Sebum May Help Lessen Acne

Acne is the cause of the misery of a lot of teens as well as several adults. This leads to many of them seeking for acne treatment and other skincare products and routines in the hopes of getting rid of and prevent acne.

A team of researchers discloses that they may have arrived at a new method to alleviating the said condition. The solution lies in skin oil, known as sebum, which is naturally produced. This research was conducted by a team headed by William Esler, a researcher at Pfizer in Cambridge, Massachusetts.

Curbing Sebum May Help Lessen Acne

Sebum is essential to the health of the skin since it aids to normalize temperature as well as keep microbes at bay, stated the team. However, the overproduction of sebum has as well long been believed to be one cause of acne. Excessive sebum could get blocked in glands, causing it to puff up and produce a bump underneath the skin. This was explained by Dr. Raman Madan, the dermatologist at Northwell Health’s Huntington Hospital. According to Dr. Madan, who wasn’t part of the new research, distinguishing a goal to lessen the production of sebum would be an innovative method to acne treatment.

The study encompassed a microscopic analysis of the skin of 22 hale and hearty participants who volunteered for the research. The team learned that sebum production of the skin depends on a certain molecular system called the de novo lipogenesis or DNL pathway.

The Findings

Majority of the sebum was discovered to be created by sebocytes, which produced the oil based on the DNL pathway’s ebb and flow. However, nine participants with acne displayed one main differentiation. The outcomes showed that when matched up to individuals having normal skin, they carry a 20% higher level of production of sebum as well as a related increase in fluxes of the DNL pathway.

Furthermore, as per the report printed in the May 15 issue of Science Translational Medicine, the team of Esler created a compound that aimed at an enzyme that has to do with the pathway. In volunteers who are healthy, the use of the treatment lessened the production of sebum by almost half.

Sure enough, these tests are early and it continues to be observed if such a compound may limit sebum (and acne) in a bigger, more thorough test.

In the interim, Dr. Madan mentioned that the given methodology “has potential.” However, he warned that this approach might be an acne treatment, not an acne cure since the cause of acne is beyond just the production of sebum. Moreover, he also said that it has the potential to be an add-on to existing acne treatments.

Dr. Michele Green also concurred that the discovery might offer possibilities to patients with acne vulgaris. Dr. Green is a dermatologist at Lenox Hill Hospital, New York City.

Young Mormons Rewarned about LDS Church’s Prohibition vs. Coffee, Vaping, Marijuana and Any Habit-Forming Substances

In light of Starbucks’ impending plan of opening its first outlet near Brigham Young University of the Mormon church, members of the Church of Jesus Christ of Latter-day Saints or LDS, particularly the youth, are rewarned about the faith’s prohibition against coffee and any drinks containing caffeine.

As reassertion and renewal of the LDS church’s warnings, a comprehensive set of new guidelines were published in the August edition of the Mormon youth magazine New Era; furnishing clear statements pertaining to the prohibitions mentioned in the church’s “Word of Wisdom.”

The reiteration stated that there are no gray areas when it comes to the prohibitions prescribed as Mormon health codes. The “Word of Wisdom’s” forbiddance encompasses all habit-forming substances including tea, vapes, cigarettes, marijuana, or any drink that includes caffeine, mocha, espresso, latte or -ccino in its product name.

The need to reiterate the LDS church’s prohibition is also in light of the concerns raised by a 2016 survey, which revealed that four (4) out of every ten (10) active Mormons below 51 years old, who responded to the survey, admitted to having drank coffee during the past six months from the date the survey was taken.

Some Key Points about the New LDS Guidelines Clarifying the Prohibited Substances

The new guidelines though made clarification that prohibition against marijuana is only if the substance is used for recreational purposes. The guidelines made mention that marijuana if medically prescribed and administered, is not forbidden. In addition, it specifically states that recommendation of marijuana as prescribed treatment must come from competent medical practitioners.

Moreover, the guidelines no longer include the hardline prohibition against entering coffee-shops like Starbucks, which for many years were regarded as taboo. Instead, young Mormons are given advise that when ordering a drink from an outlet, particularly if the shop specializes in coffee beverages, to always ask first if the concoction includes coffee, caffeine or tea as an ingredient.

Vapes, even if advertised as an alternative to conventional cigarettes, still contain nicotine and have been ascertained as addictive substitutes as well. The prohibition therefore includes vapes that come in fruity or other alluring flavors.

About the LDS Church’s “Word of Wisdom”

The “Word of Wisdom” refers to the book containing 1833 section of the Doctrine and Covenants considered by Mormon faith as compilation of revelations from God that LDS founder Joseph Smith received in 1833.

Strict compliance with the health codes set in the “Word of Wisdom” is a prerequisite for Mormon baptism, for rendering full-time missionary work, in attending Mormon church schools, and in entering LDS places of worship. Violation of the code though is not considered as ground for excommunication or any form of disciplinary action.

Aging and Other Stressors that Cause Degenerative Disc Diseases

2 Corinthians 4:16
“So we do not lose heart. Though our outer self is wasting away, our inner self is being renewed day by day.”

The gospel tells us there is honor in aging because the process normally increases wisdom through experiences. Yet the unsettling truth about growing old is that it is often accompanied by degeneration of the physical body. While the progression of degenerative disorders can be stalled, such conditions can prevent continued participation in normal day to day activities with the usual vim and vigor.

Let us cite as an example the degenerative disc disease, which happens as a person grows older. Actually, the condition is not a disease but is a disorder that occurs as part of the ageing process. Understand that parts of the spinal column are spinal discs lodged between vertebrae. A doctor may refer to them as intervertebral discs that function essentially as a cushion between each vertebra that makes up the spine.

What Happens When a Person Has Degenerative Disc Disease?

Whenever a person moves, the soft, gelatinous inner core of an intervertebral disc makes moving about and exerting force, as well as heaving or lifting loads less stressful on the spine.

Yet as a person goes through the years of performing different activities, the inner core of the intervertebral discs degenerates, eventually losing suppleness. As a result there will be friction between vertebrae on every spine movement, causing pain at the lumbar or base of the spine.

As the degenerative state advances when a person ages, weakness caused by numbness and pain radiating down to the thigh and leg will render that person less ambulatory. In severe cases of degenerative disc disease, the afflicted person loses his or her ability to walk about, without aid or assistance.

Aging though is not the only condition that leads to intervertebral degenerative discs. Obesity, strenuous labor, frequent physical work, tobacco smoking, or an injury, may result in disc degeneration. The resulting back pain may start as a slight discomfort that is initially manageable, but could worsen over time if stress is not alleviated and treated.

Conservative and Other Therapeutic Treatments

Conservative treatments of back pain caused by degenerative disc disorder include pain-relief medication and anti-inflammatory drugs. In special cases, the attending physician may prescribe muscle relaxers or steroids. Medical treatment may be accompanied by physical and/or occupational therapy, weight loss program or special exercises.

In severe or inexorable cases, surgery or medical options such as Lumbar Fusion, Epidural Steroid Injection, Disc Replacement Surgery or other similar advanced spinal treatment may be necessary.

Sufferers of back pain due to degenerative disc disorder residing in, or around Austin, Texas do not have to go far in seeking appropriate treatment. The Central Texas Spine Institute offers full services for spinal care, conservative treatment and surgery.